Check our paper in Developmental Cell on infection mounds

During infection with the intracellular bacterial pathogen L. monocytogenes, large infected domains in epithelial cell monolayers are forced to extrude to form three-dimensional mounds due to the collective and cooperative onslaught triggered by their uninfected neighbors. This mechanical competition between uninfected and bacterially-infected cells limits pathogen dissemination through the epithelium. To learn more read our paper and a really nice preview write-up that Dev. Cell gave us.